Create a free research account to view current pricing and place an order.
How does SS-31 work in research models?
SS-31 is a mitochondria-targeted tetrapeptide researched for cardiolipin interaction, mitochondrial membrane stabilization, oxidative-stress reduction, and cellular energy resilience.
What is the half-life of SS-31?
Half-life: Short-to-moderate exposure; context dependent.
Human PK varies by formulation and study context. Operationally treated as a daily mitochondrial-support signal in research settings.
Research dosing reference
5-20 mg daily depending on mitochondrial research objective and tolerance.
Dose interpretation (U-100 units)
| Target dose | U-100 units |
|---|---|
| 5 mg | 100 units |
| 10 mg | 200 units |
| 20 mg | 400 units |
Units are concentration-specific - confirm against your actual reconstitution volume.
How is SS-31 reconstituted?
| Vial | Preferred reconstitution | Final concentration |
|---|---|---|
| 10 mg | 2 mL BAC Water | 0.050 mg/unit |
| 50 mg | 3 mL BAC Water preferred for 50 mg vial; 2 mL acceptable for 10 mg vial | 0.167 mg/unit |
Injection timing
Often used earlier in the day; avoid late timing if it disrupts sleep or energy rhythm.
Beginner escalation
Begin conservatively, especially when combined with MOTS-C, NAD+, or other mitochondrial agents.
Side-effect mitigation
Monitor fatigue, headache, malaise, injection tolerance, or energy fluctuations.
Stack compatibility
Stacks conceptually with MOTS-C, NAD+, glutathione, and metabolic protocols; add one mitochondrial agent at a time when possible.
Storage & stability
Lyophilized: refrigerated or controlled cool storage. Reconstituted: refrigerated, protected from heat/light, and handled aseptically.
Protocol duration & reassessment
Mitochondrial protocols often run 4-12 weeks, followed by reassessment of fatigue, exercise tolerance, recovery, sleep, and energy consistency before continuing or repeating.
Frequently asked questions
What is SS-31 and how is it studied?
SS-31 is a mitochondria-targeted tetrapeptide researched for cardiolipin interaction, mitochondrial membrane stabilization, oxidative-stress reduction, and cellular energy resilience. SS-31 is catalogued in the Recovery / Regenerative group of this reference and is studied in laboratory and in-vitro models only. SS-31 is listed in this reference for laboratory context only; nothing here describes use in a person or animal.
What is known about the half-life of SS-31?
Reference half-life for SS-31: short-to-moderate exposure; context dependent. Human PK varies by formulation and study context. Published pharmacokinetic figures come from research and clinical-literature contexts and are listed here as reference values for laboratory work only, not as guidance for any person or animal.
How is SS-31 stored?
Lyophilized: refrigerated or controlled cool storage. Reconstituted: refrigerated, protected from heat/light, and handled aseptically. Lyophilized research peptides are generally kept cold, dry, and away from light, and reconstituted solutions are labeled with concentration and date. Follow the storage conditions documented for the specific lot you receive.
How is SS-31 reconstituted for laboratory work?
The reference reconstitution for the 10 mg vial is 2 mL BAC Water, which gives a concentration of about 5 mg/mL. Concentration equals peptide mass divided by diluent volume, so adding more liquid lowers the concentration. Add diluent slowly down the vial wall, swirl rather than shake, and confirm the arithmetic before preparing any research solution.
Is SS-31 FDA approved?
No. The research-grade SS-31 described here is an investigational, research-use-only material and is not an FDA-approved drug product. Where an approved pharmaceutical form of a compound exists, it is a separate prescription product. This reference is not medical advice, and the material is not for human or animal consumption.
All research reference · Research guides
External references: Peptide (Wikipedia) · U.S. Food and Drug Administration