Create a free research account to view current pricing and place an order.
How does TB500 work in research models?
TB-500 is a thymosin beta-4 fragment researched for actin-binding biology, cell migration, angiogenesis, tissue remodeling, and soft-tissue repair signaling. It is often paired conceptually with BPC-157 in regenerative protocols.
What is the half-life of TB500?
Half-life: Longer tissue-signaling window; human PK limited.
Human PK for TB-500 preparations is not standardized. Tissue-signaling effects are generally treated as longer-window than very short-acting peptides; twice-weekly research cadence is common.
Research dosing reference
2-5 mg two times weekly; often structured as a loading phase followed by maintenance.
Dose interpretation (U-100 units)
| Target dose | U-100 units |
|---|---|
| 2 mg | 40 units |
| 4 mg | 80 units |
| 5 mg | 100 units |
Units are concentration-specific - confirm against your actual reconstitution volume.
How is TB500 reconstituted?
| Vial | Preferred reconstitution | Final concentration |
|---|---|---|
| 10 mg | 2 mL BAC Water | 0.050 mg/unit |
| 20 mg | 2 mL BAC Water | 0.100 mg/unit |
Injection timing
Often administered two times weekly; timing can be aligned with recovery windows rather than acute effect timing.
Beginner escalation
Begin with lower weekly exposure to evaluate systemic response before increasing toward loading-style protocols.
Side-effect mitigation
Monitor injection irritation, transient fatigue, headache, flushing, or unexpected inflammatory response. Rotate sites and preserve sterile technique.
Stack compatibility
Commonly paired with complementary repair pathways such as BPC-157, TB-500, GHK-Cu, KPV, or SS-31 depending on tissue target.
Storage & stability
Lyophilized: refrigerated or controlled cool storage. Reconstituted: refrigerated, protected from heat/light, and handled aseptically.
Protocol duration & reassessment
Loading-style repair blocks commonly run several weeks, then transition to lower-frequency maintenance or discontinue after tissue-response reassessment. Avoid indefinite high-frequency repair dosing without a specific objective.
Frequently asked questions
What is TB500 and how is it studied?
TB-500 is a thymosin beta-4 fragment researched for actin-binding biology, cell migration, angiogenesis, tissue remodeling, and soft-tissue repair signaling. It is often paired conceptually with BPC-157 in regenerative protocols. TB500 is catalogued in the Recovery / Regenerative group of this reference and is studied in laboratory and in-vitro models only.
What is known about the half-life of TB500?
Reference half-life for TB500: longer tissue-signaling window; human PK limited. Human PK for TB-500 preparations is not standardized. Published pharmacokinetic figures come from research and clinical-literature contexts and are listed here as reference values for laboratory work only, not as guidance for any person or animal.
How is TB500 stored?
Lyophilized: refrigerated or controlled cool storage. Reconstituted: refrigerated, protected from heat/light, and handled aseptically. Lyophilized research peptides are generally kept cold, dry, and away from light, and reconstituted solutions are labeled with concentration and date. Follow the storage conditions documented for the specific lot you receive.
How is TB500 reconstituted for laboratory work?
The reference reconstitution for the 10 mg vial is 2 mL BAC Water, which gives a concentration of about 5 mg/mL. Concentration equals peptide mass divided by diluent volume, so adding more liquid lowers the concentration. Add diluent slowly down the vial wall, swirl rather than shake, and confirm the arithmetic before preparing any research solution.
Is TB500 FDA approved?
No. The research-grade TB500 described here is an investigational, research-use-only material and is not an FDA-approved drug product. Where an approved pharmaceutical form of a compound exists, it is a separate prescription product. This reference is not medical advice, and the material is not for human or animal consumption.
All research reference · Research guides
External references: Peptide (Wikipedia) · U.S. Food and Drug Administration